5a65ce_8be8b69e2dc54d22b984271fb607ca9e_mv2.webp

Publications

Gadadhar, Sˆ., Hirschmugl, T., & Janke, Cˆ. (2022). The tubulin code in mammalian sperm development and function. Seminars in Cell and Developmental Biology. https://doi.org/10.1016/j.semcdb.2021.12.003

ˆco-corresponding author

Gadadhar, Sˆ., Viar, G. A., Hansen, J. N., Gong, A., Kostarev, A., Ialy-Radio, C., Leboucher, S., Whitfield, M., Ziyyat, A., Touré, A., Alvarez, Lˆ., Pigino, Gˆ., & Janke, Cˆ. (2021). Tubulin glycylation controls axonemal dynein activity, flagellar beat, and male fertility. Science, 371(6525). https://doi.org/10.1126/science.abd4914

ˆco-corresponding author, highlighted on the cover of Science

Bodakuntla, S., Yuan, X., Genova, M., Gadadhar, S., Leboucher, S., Birling, M.-C., Klein, D., Martini, R., Janke, C., & Magiera, M. M. (2021). Distinct roles of α- and β-tubulin polyglutamylation in controlling axonal transport and in neurodegeneration. EMBO Journal, 40(17). https://doi.org/10.15252/embj.2021108498

Giordano, T*., Gadadhar, S*., Bodakuntla, S., Straub, J., Leboucher, S., Martinez, G., Chemlali, W., Bosc, C., Andrieux, A., Bieche, I., Arnoult, C., Geimer, S., & Janke, C. (2019). Loss of the deglutamylase CCP5 perturbs multiple steps of spermatogenesis and leads to male infertility. Journal of Cell Science, 132(3). https://doi.org/10.1242/jcs.226951

*equal contribution

Magiera, M. M., Singh, P., Gadadhar, S., & Janke, C. (2018). Tubulin Posttranslational Modifications and Emerging Links to Human Disease. Cell, 173(6), 1323–1327. https://doi.org/10.1016/j.cell.2018.05.018

Gadadhar, S., Dadi, H., Bodakuntla, S., Schnitzler, A., Bièche, I., Rusconi, F., & Janke, C. (2017). Tubulin glycylation controls primary cilia length. Journal of Cell Biology, 216(9), 2701–2713. https://doi.org/10.1083/jcb.201612050

Gadadhar, S., Bodakuntla, S., Natarajan, K., & Janke, C. (2017). The tubulin code at a glance. Journal of Cell Science, 130(8), 1347–1353. https://doi.org/10.1242/jcs.199471

Natarajan, K., Gadadhar, S., Souphron, J., Magiera, M. M., & Janke, C. (2017). Molecular interactions between tubulin tails and glutamylases reveal determinants of glutamylation patterns. EMBO Reports, 18(6), 1013–1026. https://doi.org/10.15252/embr.201643751

Grau, M. B., Masson, C., Gadadhar, S., Rocha, C., Tort, O., Sousa, P. M., Vacher, S., Bieche, I., & Janke, C. (2017). Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration. Journal of Cell Science, 130(5), 938–949. https://doi.org/10.1242/jcs.199091

Gadadhar, S., Bora, N., Tiwari, V., & Karande, A. A. (2014). Sequestration of the abrin A chain to the nucleus by BASP1 increases the resistance of cells to abrin toxicity. Biochemical Journal, 458(2), 375–385. https://doi.org/10.1042/bj20131110

Goswami, T. K., Gadadhar, S., Balaji, B., Gole, B., Karande, A. A., & Chakravarty, A. R. (2014). Ferrocenyl-l-amino acid copper(ii) complexes showing remarkable photo-induced anticancer activity in visible light. Dalton Transactions, 43(31), 11988–11999. https://doi.org/10.1039/c4dt01348d

Gadadhar, S., & Karande, A. A. (2013). Abrin Immunotoxin: Targeted Cytotoxicity and Intracellular Trafficking Pathway. PLoS ONE, 8(3). https://doi.org/10.1371/journal.pone.0058304

Goswami, T. K., Gadadhar, S., Karande, A. A., & Chakravarty, A. R. (2013). Photocytotoxic ferrocene-appended (l-tyrosine)copper(II) complexes of phenanthroline bases. Polyhedron, 52, 1287–1298. https://doi.org/10.1016/j.poly.2012.06.018

Goswami, T. K., Gadadhar, S., Gole, B., Karande, A. A., & Chakravarty, A. R. (2013). Photocytotoxicity of copper(II) complexes of curcumin and N-ferrocenylmethyl-l-amino acids. European Journal of Medicinal Chemistry, 63, 800–810. https://doi.org/10.1016/j.ejmech.2013.03.026

Goswami, T. K., Gadadhar, S., Roy, M., Nethaji, M., Karande, A. A., & Chakravarty, A. R. (2012). Ferrocene-conjugated copper(II) complexes of l -methionine and phenanthroline bases: Synthesis, structure, and photocytotoxic activity. Organometallics, 31(8), 3010–3021. https://doi.org/10.1021/om201102k

Maity, B., Gadadhar, S., Goswami, T. K., Karande, A. A., & Chakravarty, A. R. (2012). Photo-induced anticancer activity of polypyridyl platinum(II) complexes. European Journal of Medicinal Chemistry, 57, 250–258. https://doi.org/10.1016/j.ejmech.2012.09.025

Hussain, A., Gadadhar, S., Goswami, T. K., Karande, A. A., & Chakravarty, A. R. (2012). Photo-induced DNA cleavage activity and remarkable photocytotoxicity of lanthanide(iii) complexes of a polypyridyl ligand. Dalton Transactions, 41(3), 885–895. https://doi.org/10.1039/c1dt11400j

Hussain, A., Gadadhar, S., Goswami, T. K., Karande, A. A., & Chakravarty, A. R. (2012). Photoactivated DNA cleavage and anticancer activity of pyrenyl-terpyridine lanthanide complexes. European Journal of Medicinal Chemistry, 50, 319–331. https://doi.org/10.1016/j.ejmech.2012.02.011

Maity, B., Gadadhar, S., Goswami, T. K., Karande, A. A., & Chakravarty, A. R. (2011). Impact of metal on the DNA photocleavage activity and cytotoxicity of ferrocenyl terpyridine 3d metal complexes. Dalton Transactions, 40(44), 11904–11913. https://doi.org/10.1039/c1dt11102g

Bora, N., Gadadhar, S., & Karande, A. A. (2010). Signaling different pathways of cell death: Abrin induced programmed necrosis in U266B1 cells. International Journal of Biochemistry and Cell Biology, 42(12), 1993–2003. https://doi.org/10.1016/j.biocel.2010.08.012