The Team
Who We Are
Sudarshan Gadadhar
Principal Investigator
Postdoc, Institut Curie, Paris
PhD., Indian Institute of Science, Bangalore
I trained as a biochemist and cell biologist during my PhD in Prof. Anjali Karande's lab at the Indian Institute of Science, working on developing immunotoxins for targeted cancer therapy. I then moved to Institut Curie for my postdoctoral research in Prof. Carsten Janke's lab where I studied the role of tubulin posttranslational modifications in regulating motile cilia and flagella in mammals. I continue to understand the tubulin code and its impact on mammalian cilia and flagella.
Work aside, I am an amateur photographer, with a penchant for music.
I hold a Master's degree in Molecular biology from Yuvaraja's College, University of Mysore. As part of my Masters' thesis dissertation, I worked on Analysis of PIP4K2A Interaction with Eukaryotic Translation Initiation Factor 4E Binding Protein-1 (eIF4EBP1) in Dr Vasudevan Seshadri's lab at the National Centre for Cell Science, Pune. Currently, I am studying how tubulin glutamylation and glycylation regulate microtubule-protein interactions in cilia using biochemical and in vitro approaches with purified components.
In my free time, I explore historical places admiring the ancient knowledge and marvels of art and architecture
I did my MSc in Molecular biology and Human genetics from Manipal Academy of Higher Education (MAHE), Manipal. I then joined as an intern in Prof. Colin Jamora's lab at the Institute for Stem Cell Science and Regenerative Medicine (inStem), where I worked on wound healing and hair follicle neogenesis. I'm currently investigating the role of two tubulin PTMs, glutamylation and glycylation affect processes within primary cilia in different ciliating cells.
I completed my Master's in Biotechnology from St. Xavier's College, Kolkata. My dissertation thesis in Prof. Debashis Mukhopadhyay's lab at Saha Institute of Nuclear Physics, Kolkata focussed on the Functional Classification of Long Non-Coding RNAs associated with Huntington's Disorder. As a graduate student in Dr. Sudarshan Gadadhar's lab at inStem, I am focussing to understand the importance of tubulin posttranslational modification, glycylation, in regulating structure-functions of mammalian cilia and flagella.
Apart from academia, I am a professional Bharatnatyam dancer (You can find me dancing anytime, anywhere!) I also love reading classics and have an affinity for writing!
I completed Bachelor of Science (B.Sc. Honours) in Microbiology from St. Xavier's College, Kolkata and Master of Science (M.Sc.) in Biophysics and Molecular Biology from University of Calcutta. My Masters' dissertation thesis in Dr. Sumita Sengupta's lab at the Department of Biophysics, Molecular Biology and Bioinformatics, University of Calcutta, I investigated the role of micro-RNAs in the regulation of autophagy initiation in breast cancer cell line. As a graduate student in Dr. Sudarshan Gadadhar's lab at inStem I am interested in determining how tubulin glutamylation regulates molecular processes in mammalian cilia and establish mechanistic links between perturbed tubulin glutamylation, cilia functions and specific human disorders.
Apart from science, I find my peace in singing and listening to good music. I am often found humming the tunes of my favourite songs while working in the lab. I also love to engage myself in doodling, sketching and watching crime thrillers
